Tizanidine is used for:

Treating muscle spasms. It may also be used to treat other conditions as determined by your doctor.

Tizanidine is a skeletal muscle relaxant. It works by blocking nerves that stimulate muscles to contract.

Do NOT use Tizanidine if:

• you are allergic to any ingredient in Tizanidine
• you are taking fluvoxamine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tizanidine :

Some medical conditions may interact with Tizanidine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have liver or kidney problems or prostate problems

Some MEDICINES MAY INTERACT with Tizanidine. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Alpha₂-agonists (eg, clonidine), fluvoxamine, or medicines that act on the liver (eg, amiodarone, cimetidine, ciprofloxacin, ticlopidine) because the actions and side effects of these medicines may be increased
• Birth control pills because the effectiveness of Tizanidine may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tizanidine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tizanidine :

Use Tizanidine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Food can change the way your body absorbs and uses Tizanidine. Be sure to discuss this with your doctor to determine the best way to take your dose, especially when changes to your dose are being considered, or if you are being prescribed a different dose form of Tizanidine (eg, tablets or capsules).
• Do not stop taking Tizanidine suddenly. If Tizanidine is stopped, the dose should be reduced slowly to prevent symptoms of withdrawal, including high blood pressure, fast heartbeat, tremor, anxiety, and muscle tension.
• If you miss a dose of Tizanidine , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tizanidine.

Important safety information:

• Tizanidine may cause drowsiness, dizziness, lightheadedness, or fainting. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Tizanidine.
• Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Tizanidine. Tizanidine will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
• Tizanidine may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Tizanidine.
• Little or no information is available on the possible side effects from long-term use (more than 1 year) of high single doses above 8 mg or multiple doses above 24 mg a day.
• LAB TESTS, such as liver tests, may be performed to check for side effects. Be sure to keep all doctor and lab appointments.
• Use Tizanidine with caution in the ELDERLY because they may be more sensitive to its effects.
• Use Tizanidine with extreme caution in CHILDREN; safety and effectiveness have not been confirmed.
• PREGNANCY and BREAST-FEEDING: It is unknown if Tizanidine causes harm to the developing fetus. If you become pregnant, discuss with your doctor the benefits and risks of using Tizanidine during pregnancy. It is unknown if Tizanidine is excreted in breast milk. If you are or will be breast-feeding while you are using Tizanidine , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Tizanidine :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth; flushing; tiredness; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in emotions, mood, or behavior; hallucinations; increased muscle spasms; muscle weakness; slow heartbeat; trouble urinating or lack of bladder control; urinary tract infection; yellowing of the skin or eyes.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.